Search results for "Cotton effect"
showing 2 items of 2 documents
Interactions of benzodiazepines with human serum albumin. Circular dichroism studies.
1973
The circular dichroism spectra of 12 benzodiazepine derivatives studied in presence of human serum albumin are presented. Nearly all substances give biphasic extrinsic Cotton effects. At the CD maxima the molar ellipticities and the anisotropy factors are calculated. The influence of the chemical structure of the benzodiazepines on the induced Cotton effect is discussed. There is a linear correlation between the anisotropy factors and the logarithms of the partition coefficients of the substances. It is suggested that the phenyl ring of the benzodiazepine molecule is one of the essential groups for the binding of these substances to human serum albumin.
Rotationsdispersion bei monomeren und polymeren L-bornylestern
1962
L-Bornylacrylat und -methacrylat wurden unter verschiedenen Bedingungen radikalisch und ionisch polymerisiert. Die Wellenlangenabhangigkeit der Drehwerte last sich durch eine eintermige DRUDE-Gleichung beschreiben. Die DRUDE-Konstanten fur Poly-L-bornylacrylat hangen nur wenig vom Losungsmittel ab. Sie werden aber, ebenso wie die Lage der COTTON-Effekte, vom Polymerisationsmechanismus beeinflust. The radical and ionic polymerization of L-bornylacrylate and -methacrylate was studied under varying conditions. The optical rotatory dispersion is represented by a simple one-term DRUDE equation. The solvents have little effect on the DRUDE constants for poly-L-bornylacrylate. However, these const…